Copper-67
Copper-67 (Cu-67) is a short-range, beta-emitting radioisotope which is attractive for medical purposes due to its ability to carry sufficient radiation energy to cause cell death in targeted cells while having a short half-life, limiting unwanted radioactivity in otherwise healthy tissue.
We are routinely producing Cu-67 to ensure expanded and reliable supply of this promising radioisotope for the treatment of cancer.
A NOVEL APPROACH
TO CANCER THERAPY
Development of Cu-67 has also been hampered by the lack of chelators that securely attach copper to its targeted molecule. Clarity Pharmaceuticals’ Targeted Copper Theranostics platform using chelators that securely hold copper, is now reaching later stage development and commercialization and will treat cancers such as neuroblastoma, breast and prostate.
Scalable, Reliable,
Domestic Production Processes
NorthStar’s unique and proprietary electron Accelerator Production facility and processes are designed to provide efficiencies throughout the production process, thereby enabling the production of multiple radioisotopes utilizing the same equipment.
Our 30,000 sq. ft. state-of-the- art Accelerator Production facility houses two Rhodotron TT300 Electron Accelerators. This advanced technology will produce clean, commercial quantities of Cu-67 and is environmentally friendly and non-uranium based. The manufacturing process has no long-lived contaminants or byproducts and its starting material, zinc, is readily available. This clean manufacturing process allows for high volume production, with no issues associated with access to stable target material or generation of long-lived radioactive waste.
- Unique, proprietary facility and processes designed to provide efficiencies that enable production of multiple radioisotopes utilizing the same equipment
- Routinely produced using an electron accelerator
- Beta emitter with a 61.8–hour half-life
- Cu-67 therapeutic companion to Cu-64 (diagnostic)
Fact Sheet
Cu-64 SAR-bisPSMA PET/CT imaging before and after a single cycle of 8GBq Cu-67 SAR-bisPSMA (cohort 2)
(photo courtesy of Clarity Pharmaceuticals)
